May 28, 2025
Metformin: Miracle aging drug or overhyped hope?
Siddhartha JanaWhat is Metformin?
Metformin is an FDA-approved drug for Type 2 diabetes, also used for weight loss and PCOS. Some doctors believe it may prevent chronic diseases and support longevity.
Source: Canva
Possible anti-aging benefits
Early research hints metformin might delay aging-related diseases like cancer, dementia, and heart issues by reducing inflammation and repairing tissues.
Source: Canva
Mixed research results
Animal studies on metformin’s lifespan benefits are inconsistent, and human studies mostly focus on diabetic patients, showing conflicting outcomes.
Source: Canva
Limited evidence for longevity
Experts agree metformin’s life-extending benefits for healthy people remain unproven. Some data shows short-term mortality reduction, but long-term effects are unclear.
Source: Canva
Awaiting major human trial
The T.A.M.E. Trial aims to test metformin’s impact on aging in healthy older adults, but delays mean results could take years.
Source: Canva
Low cost, mild side effects
Metformin is affordable and generally safe. Common side effects include digestive issues and possible muscle-building challenges, usually mild and reversible.
Source: Canva
Behavior boost or real effect?
Some users say metformin motivates them to adopt healthier habits like diet tracking and regular exercise, possibly influencing results more than the drug itself.
Source: Canva
Expert caution
While metformin may help those at risk of diabetes, experts warn against assuming anti-aging effects in healthy individuals without stronger evidence.
Source: Canva
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